908256-56-4

Basic information

• Product Name: ethyl 2-hydroxy-3-[1-oxo-3-(2-trifluoromethylphenyl)-1,2-dihydroisoquinolin-7-ylamino]propanoate
• Synonyms: ethyl 2-hydroxy-3-[1-oxo-3-(2-trifluoromethylphenyl)-1,2-dihydroisoquinolin-7-ylamino]propanoate
• CAS NO: 908256-56-4
• Molecular Weight: 420.388
• Mol File: 908256-56-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-hydroxy-3-[1-oxo-3-(2-trifluoromethylphenyl)-1,2-dihydroisoquinolin-7-ylamino]propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-hydroxy-3-[1-oxo-3-(2-trifluoromethylphenyl)-1,2-dihydroisoquinolin-7-ylamino]propanoate(908256-56-4)
• EPA Substance Registry System: ethyl 2-hydroxy-3-[1-oxo-3-(2-trifluoromethylphenyl)-1,2-dihydroisoquinolin-7-ylamino]propanoate(908256-56-4)

Safety Data

• Hazardous Substances Data: 908256-56-4(Hazardous Substances Data)

Upstream product

• 4538-50-5 methyl glycidate 
• 862470-02-8 7-amino-3-(2-trifluoromethylphenyl)-2H-isoquinolin-1-one 

Downstream Products

• 908256-55-3 ethyl 2-oxo-3-[1-oxo-3-(2-trifluoromethylphenyl)-1,2-dihydroisoquinolin-7-yl]oxazolidine-5-carboxylate 

Relevant articles and documents

1-(2H)-ISOQUINOLONE DERIVATIVE

The present invention provides a compound having high antitumor activity, which is useful for therapeutic and preventive agents effective for proliferative diseases such as cancer; a production method thereof; an intermediate compound useful for such production; and a pharmaceutical composition comprising such a compound. The present invention provides a compound represented by the formula (1): wherein X represents an aryl group or heteroaryl group which may be substituted, Cy represents a 4- to 7-membered monocyclic heterocyclic ring or a 8- to 10-membered condensed heterocyclic ring which may be substituted, and Z represents O, S, or NRa; or a prodrug thereof; or a pharmaceutically acceptable salt thereof; and a pharmaceutical and a pharmaceutical composition which comprise the compound.