90832-25-0

Basic information

• Product Name: 5H-Pyrazolo[5,1-b][1,3]oxazine, 3,3a,6,7-tetrahydro-3,3,6,6-tetramethyl-
• CAS NO: 90832-25-0
• Molecular Formula: C10H18N2O
• Molecular Weight: 182.266
• Mol File: 90832-25-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5H-Pyrazolo[5,1-b][1,3]oxazine, 3,3a,6,7-tetrahydro-3,3,6,6-tetramethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Pyrazolo[5,1-b][1,3]oxazine, 3,3a,6,7-tetrahydro-3,3,6,6-tetramethyl-(90832-25-0)
• EPA Substance Registry System: 5H-Pyrazolo[5,1-b][1,3]oxazine, 3,3a,6,7-tetrahydro-3,3,6,6-tetramethyl-(90832-25-0)

Safety Data

• Hazardous Substances Data: 90832-25-0(Hazardous Substances Data)

Upstream product

• 4136-44-1 3,3,7,7-Tetramethyl-1,5-diazabicyclo<3.3.0>octan-2,6-dion 
• 27219-76-7 3,3,3',3'-Tetramethyl<1,1'-biazetidine>-2,2'-dione 

Relevant articles and documents

Michael addition of N-isobutylidene-t-butylamine to dimethyl methoxymethylenemalonate and a new synthesis of some fused pyrazole derivatives from the adduct

N-Isobutylidenemethylamine reacted with dimethyl methoxymethylenemalonate to afford the N-alkylation product 3a exclusively. Exchanging the N- substituent of the Schiff's base from methyl to t-butyl altered the course of the reaction, allowing Michael addition to take place predominantly. The Michael adduct 4c on reaction with hydrazinoalkanols 6a,b, 6c,d and 6e gave tetrahydropyrazolo[5,1-b]oxazoles 9a,b, tetrahydropyrazolo[5,1- b][1,3]oxazines 9c,d and hexahydropyrazolo[5,1-b][1,3]oxazepine 9e, respectively.