908351-31-5 Usage
General Description
AEB 071, also known as sotrastaurin, is a chemical compound that acts as a potent and selective protein kinase C (PKC) inhibitor. It has shown potential in the treatment of various autoimmune and inflammatory diseases, as well as in preventing organ transplant rejection. AEB 071 works by inhibiting the activity of PKC, which plays a crucial role in the regulation of immune response and inflammation. Research studies have demonstrated the efficacy of AEB 071 in reducing symptoms and disease progression in conditions such as psoriasis, rheumatoid arthritis, and multiple sclerosis. Additionally, it has shown promise in improving the success rates of organ transplants by preventing graft rejection. AEB 071 is currently being investigated in clinical trials for its potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 908351-31-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,8,3,5 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 908351-31:
(8*9)+(7*0)+(6*8)+(5*3)+(4*5)+(3*1)+(2*3)+(1*1)=165
165 % 10 = 5
So 908351-31-5 is a valid CAS Registry Number.
908351-31-5Relevant articles and documents
CRYSTAL MODIFICATIONS -3- (1H-IND0L-3-YL) -4- [2- (4-METHYL-PIPERAZIN-1-YL) -QUINAZOLIN-4-YL] -PYRROLE-2, 5-D IONE
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Page/Page column 14-15, (2008/12/05)
The invention relates to a new crystalline form of the acetate salt of, 3-(1.H.-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, which may be used for example for transplantation.