908382-45-6

Basic information

• Product Name: 2H-Imidazole-2-thione, 4-(4-fluorophenyl)-5-(2-fluoro-4-pyridinyl)-1,3-dihydro-1-(2-methoxyethyl) -
• CAS NO: 908382-45-6
• Molecular Formula: C17H15F2N3OS
• Molecular Weight: 347.388
• Mol File: 908382-45-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Imidazole-2-thione, 4-(4-fluorophenyl)-5-(2-fluoro-4-pyridinyl)-1,3-dihydro-1-(2-methoxyethyl) -(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Imidazole-2-thione, 4-(4-fluorophenyl)-5-(2-fluoro-4-pyridinyl)-1,3-dihydro-1-(2-methoxyethyl) -(908382-45-6)
• EPA Substance Registry System: 2H-Imidazole-2-thione, 4-(4-fluorophenyl)-5-(2-fluoro-4-pyridinyl)-1,3-dihydro-1-(2-methoxyethyl) -(908382-45-6)

Safety Data

• Hazardous Substances Data: 908382-45-6(Hazardous Substances Data)

Upstream product

• 1015445-69-8 1-(4-fluorophenyl)-2-(2-fluoro-4-pyridyl)-2-[(2-methoxyethyl)amino]ethanone hydrochloride 
• 333-20-0 potassium thioacyanate 
• 556-64-9 methyl thiocyanate 
• 1015514-21-2 1-(4-fluorophenyl)-2-(2-fluoro-4-pyridyl)-2-[(2-methoxyethyl)amino]ethanone 
• 908382-44-5 2-fluoro-4-[4-(4-fluorophenyl)-1-(2-methoxyethyl)-3-oxido-1H-imidazol-5-yl]pyridine 

Downstream Products

• 1015445-85-8 3-[4-(4-fluorophenyl)-5-(2-fluoro-4-pyridyl)-1-(2-methoxyethyl)-1H-imidazol-2-ylsulfanyl]propane-1,2-diol 
• 1015445-84-7 4-[2-(benzylsulfanyl)-4-(4-fluorophenyl)-1-(2-methoxyethyl)-1H-imidazol-5-yl]-2-fluoropyridine 
• 908381-35-1 2-fluoro-4-[4-(4-fluorophenyl)-1-(2-methoxyethyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]pyridine 

Relevant articles and documents

Regiospecific and highly flexible synthesis of 1,4,5-trisubstituted 2-sulfanylimidazoles from structurally diverse ethanone precursors

Imidazoles represent important bioactive scaffolds in medicinal chemistry. More than 2,500 structures are listed in drug discovery databases and over 3,000 patents have been claimed for imidazole-based structures. Recent imidazole pharmacophores have targ

2-SULFINYL- AND 2-SULFONYL-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS

The invention relates to 2-sulfinyl- or 2-sulfonyl-substituted imidazole derivatives of the formula (I) in which the radicals R1, R2, R3 and R4 have the meaning indicated in the description. The compounds of the