908589-91-3Relevant articles and documents
T3P-Promoted, Mild, One-Pot Syntheses of Constrained Polycyclic Lactam Dipeptide Analogues via Stereoselective Pictet-Spengler and Meyers Lactamization Reactions
Jida, Mouhamad,Van Der Poorten, Olivier,Guillemyn, Karel,Urbanczyk-Lipkowska, Zofia,Tourwé, Dirk,Ballet, Steven
supporting information, p. 4482 - 4485 (2015/09/28)
A new convenient, mild, one-pot procedure is described for the diastereoselective synthesis of constrained 7,5- and 7,6-fused azabicycloalkanes. Using 2-formyl-L-tryptophan and 2-formyl-l-phenylalanine as bielectrophilic building blocks, T3P-mediated Pict
Synthesis and evaluation of the β-turn properties of 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-ones and of their spirocyclic derivative
Van Rompaey, Karolien,Ballet, Steven,Toemboely, Csaba,De Wachter, Rien,Vanommeslaeghe, Kenno,Biesemans, Monique,Willem, Rudolph,Tourwe, Dirk
, p. 2899 - 2911 (2007/10/03)
A series of 4-amino-tetrahydro-2-benzazepin-3-one derivatives (Ac-Aba-Xxx-NHMe) were prepared as tetrapeptide mimetics. Considering the structural resemblance with the so-called Freidinger lactams, their propensity to adopt a β-turn conformation was inves
