908852-19-7 Usage
General Description
Atorvastatin methanamine salt is a chemical compound that combines atorvastatin, a medication used to lower cholesterol and reduce the risk of heart disease, with methanamine, a compound used as a stabilizing agent. Atorvastatin works by inhibiting an enzyme in the liver that plays a key role in the production of cholesterol, while methanamine helps to stabilize the compound for use as a medication. This combination allows for better stability and effectiveness of atorvastatin when used as a medication, ultimately aiding in the treatment and prevention of cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 908852-19-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,8,8,5 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 908852-19:
(8*9)+(7*0)+(6*8)+(5*8)+(4*5)+(3*2)+(2*1)+(1*9)=197
197 % 10 = 7
So 908852-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C33H35FN2O5.C33H34FN2O5.CH5N.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;1-2;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);3-16,21,26-27,37H,17-20H2,1-2H3,(H,35,41)(H,39,40);2H2,1H3;/q;-1;;+2/p-1/t2*26-,27-;;/m11../s1
908852-19-7Relevant articles and documents
Process for producing atorvastatin hemicalcium
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Page/Page column 8, (2008/06/13)
A process is provided for preparing pharmaceutical grade atorvastatin hemicalcium salt comprising: (a) deesterifying, wherein R is an ester protecting group to (b) extracting R(R*,R*)-3 into an organic solvent or mixture of solvents, (c) adding a base of formula NR1R2R3 wherein R1, R2 and R3 are independently selected from H, substituted or non-substituted C1 to C7 alkyl, C6 to C9 aryl, C8 to C10 aralkyl or aminoalkyl to form atorvastatin base salt, (d) isolating by precipitation of the above atorvastatin base salt and purifying when necessary,