90916-79-3

Basic information

• Product Name: 2-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-6-methylpyrimidin-4(1H)-one
• CAS NO: 90916-79-3
• Molecular Formula: C₁₀H₁₀N₄O₂
• Molecular Weight: 218.212
• Mol File: 90916-79-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 355.465°C at 760 mmHg
• Flash Point: 168.779°C
• Density: 1.378g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 2-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-6-methylpyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-6-methylpyrimidin-4(1H)-one(90916-79-3)
• EPA Substance Registry System: 2-[(2E)-2-(furan-2-ylmethylidene)hydrazinyl]-6-methylpyrimidin-4(1H)-one(90916-79-3)

Safety Data

• Hazardous Substances Data: 90916-79-3(Hazardous Substances Data)

Usage

Molecular Structure

A pyrimidine ring with a methyl group at the 6th position and a hydrazinyl group attached to a furan ring at the 2nd position.

Mechanism of Action

Inhibits the enzyme xanthine oxidase, which is responsible for the conversion of hypoxanthine to xanthine and xanthine to uric acid.

Indications

Used in the treatment of chronic gout and hyperuricemia.

Form

Oral tablet.

Side Effects

May cause nausea, rash, and liver problems in some individuals.

Advantages

Generally well-tolerated and a valuable option for managing chronic gout and hyperuricemia, especially for those who cannot tolerate or do not respond to other medications.

Upstream product

• 98-01-1 furfural 
• 37893-08-6 2-hydrazino-6-methylpyrimidin-4(3H)-one 

Relevant articles and documents

Pyrimidine derivative with anticancer effect

The invention relates to a pyrimidine derivative with an anticancer effect, belonging to the field of chemical medicines. The invention provides an application of a compound as shown in a formula I which is described in the specification or pharmaceutical