90926-25-3

Basic information

• Product Name: 1-methyl-4-(propylsulfonyl)benzene
• CAS NO: 90926-25-3
• Molecular Formula: C₁₀H₁₄O₂S
• Molecular Weight: 198.282
• Mol File: 90926-25-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 336.5°C at 760 mmHg
• Flash Point: 185.5°C
• Density: 1.098g/cm³
• Vapor Pressure: 0.000218mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 1-methyl-4-(propylsulfonyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-(propylsulfonyl)benzene(90926-25-3)
• EPA Substance Registry System: 1-methyl-4-(propylsulfonyl)benzene(90926-25-3)

Safety Data

• Hazardous Substances Data: 90926-25-3(Hazardous Substances Data)

Usage

General Description

1-methyl-4-(propylsulfonyl)benzene is a chemical compound with the molecular formula C10H14O2S. It is a sulfone derivative of benzene, with a methyl group and a propylsulfonyl group attached to the benzene ring. 1-methyl-4-(propylsulfonyl)benzene is commonly used in organic synthesis and chemical research as a building block for creating more complex molecules. It is also used as a starting material for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The propylsulfonyl group in 1-methyl-4-(propylsulfonyl)benzene provides enhanced reactivity and stability, making it a versatile compound in various chemical processes. Overall, this compound is important in the field of organic chemistry and has applications in the manufacturing of a wide range of products.

Upstream product

• 5366-49-4 4-toluenesulfonylacetone 
• 32228-15-2 (E)-p-tolyl-1-propenyl sulfone 
• 24599-52-8 4-methylphenyl propyl sulfide 
• 106-94-5 propyl bromide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 107-08-4 1-iodo-propane 
• 136384-88-8 isopropylidene 5-tosyloxymalonate 
• 3112-87-6 1-methyl-4-(prop-2-ene-1-sulfonyl)benzene 
• 351186-41-9 4-methyl-N-morpholin-4-ylbenzenesulfonamide 
• 624-31-7 4-tolyl iodide 
• 5720-05-8 4-methylphenylboronic acid 
• 599-91-7 propyl tosylate 

Downstream Products

• 99186-88-6 4-Propylsulfonyl-benzoesaeure 
• 100973-05-5 1-diacetoxymethyl-4-(propane-1-sulfonyl)-benzene 
• 154581-54-1 (E/Z)-1-benzyloxy-3-(4-tolylsulfonyl)pentene 
• 855290-50-5 4-(propylsulfonyl)benzonitrile 
• 1671-31-4 5-Propylsulfonyl-2-methyl-benzolsulfonamid 
• 1671-32-5 5-Propylsulfonyl-2-methyl-benzolsulfonsaeure-⁽¹⁾-methylamid 
• 1671-33-6 5-Propylsulfonyl-2-methyl-benzol-sulfonsaeure-⁽¹⁾-anilid 
• 1671-35-8 5-Propylsulfonyl-2-methyl-benzol-sulfonsaeure-(1)-<3-chlor-anilid> 
• 1671-34-7 5-Propylsulfonyl-2-methyl-benzol-sulfonsaeure-(1)-<2-chlor-anilid> 
• 1240287-04-0 2-bromo-1-methyl-4-(propylsulfonyl)benzene 
• 1240287-05-1 tert-butyl {4-chloro-2-[(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy}acetate 
• 1240285-45-3 {4-chloro-2-[(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy}acetic acid 
• 153651-86-6 5,11,17,23-tetrakis(chloromethyl)-25,26,27,28-tetrapropoxycalix[4]arene 

Relevant articles and documents

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

Aryl alkyl sulfone compound and reducing coupling method for constructing sulfone compounds

The invention discloses an aryl alkyl sulfone compound shown as a formula (1) and a synthetic method thereof. The aryl alkyl sulfone compound is prepared by taking an aromatic iodide, an inorganic sulfur reagent and an alkyl bromide as reaction raw materials to carry out reacting in a solvent under action of alkali, a catalyst, a ligand, a reducing agent and an additive. According to the invention, an inorganic sulfur reagent is used as a sulfur source to construct the aryl alkyl sulfone compound in one step under catalysis and reduction conditions, so that the defect in synthesizing the arylalkyl sulfone compound by conventional oxidation of thioether is avoided. The aryl alkyl sulfone compound developed by the invention can be used for synthesizing aryl alkyl sulfone medicines.

One-pot three-component sulfone synthesis exploiting palladium-catalysed aryl halide aminosulfonylation

A palladium-catalysed aminosulfonylation process is used as the key-step in a one-pot, three-component sulfone synthesis. The process combines aryl-, heteroaryl- and alkenyl iodides with a sulfonyl unit and an electrophilic coupling fragment. The sulfonyl unit is delivered in the form of an aminosulfonamide, which then serves as a masked sulfinate. The sulfinate is combined, in situ, with an electrophilic coupling partner, such as a benzylic, allylic or alkyl halide, an electron-poor arene, or a cyclic epoxide, to provide the corresponding sulfone products in good to excellent yields. The mild reaction conditions and use of commercially available reaction components allows the easy preparation of a broad range of sulfones featuring a variety of functional groups. The process obviates the need to employ thiol starting materials, and oxidative operations.