909365-96-4

Basic information

• Product Name: 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one
• Synonyms: 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one
• CAS NO: 909365-96-4
• Molecular Weight: 316.154
• Mol File: 909365-96-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one(909365-96-4)
• EPA Substance Registry System: 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one(909365-96-4)

Safety Data

• Hazardous Substances Data: 909365-96-4(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 665033-14-7 4-bromo-2-(phenylethynyl)aniline 
• 103-80-0 phenylacetyl chloride 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 452349-62-1 methyl 5-bromo-2-(2-phenylacetamido)benzoate 

Downstream Products

• 1610555-88-8 6-bromo-4-butoxy-3-phenyl-2(1H)-quinolinone 
• 1600565-89-6 4-chloro-6-((4-chlorophenyl)(1,2-dimethyl-1H-imidazol-5-yl)(hydroxy)methyl)-3-phenylquinoline-2-carbonitrile trifluoroacetate 
• 1600565-79-4 C₂₈H₁₈ClN₅O 
• 1600565-80-7 C₂₈H₁₈ClN₅O 
• 1600565-78-3 6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-3-phenylquinoline-2,4-dicarbonitrile 
• 1600565-77-2 (4-chlorophenyl)(2,4-dimethoxy-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)methanol trifluoroacetate 
• 1600565-75-0 4-chloro-6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-3-phenylquinoline-2-carbonitrile 
• 1600565-74-9 (4-chloro-2-(dimethylamino)-3-phenylquinolin-6-yl)(4-chlorophenyl)(3-methylisoxazol-5-yl)methanol trifluoroacetate 
• 1600565-70-5 (2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(3-methylisoxazol-5-yl)methanol trifluoroacetate 
• 1600565-68-1 (2,4-dichloro-3-phenylquinolin-6-yl)(6-methoxypyridin-3-yl)(3-methylisoxazol-5-yl)methanol trifluoroacetate 
• 1600565-63-6 (2,4-dichloro-3-phenylquinolin-6-yl)(3,5-dimethylisoxazol-4-yl)(6-methoxypyridin-3-yl)methanol trifluoroacetate 
• 1600565-50-1 (2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-2-yl)(pyridazin-4-yl)methanol 
• 1600565-49-8 (2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyrimidin-5-yl)methanol 
• 1600565-48-7 (4-chlorophenyl)(2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)methanol 

Relevant articles and documents

ALKYL LINKED QUINOLINYL MODULATORS OF RORγt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of FormulaI.wherein:R1, R2, R3, R4, R5, R6, R7, R8, and R9are defined in the specification.The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

ALKYL LINKED QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.