90946-83-1Relevant articles and documents
A different role of Meldrum's acid in the Biginelli reaction
Svetlik, Jan,Veizerova, Lucia
experimental part, p. 199 - 205 (2011/04/17)
A Biginelli-type condensation using Meldrum's acid has been accomplished in refluxing AcOH to give 6-substituted dihydropyrimidine-2,4-(1H,3H)-diones. In contrast to other aldehydes, the three-component reaction with salicylaldehyde led to an oxygen-bridged pyridine. A reaction mechanism is proposed.