909786-44-3Relevant articles and documents
General synthesis of β-alanine-containing spider polyamine toxins and discovery of Nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors
Lucas, Simon,Poulsen, Mette H.,N?rager, Niels G.,Barslund, Anne F.,Bach, Tinna B.,Kristensen, Anders S.,Str?mgaard, Kristian
supporting information, p. 10297 - 10301 (2013/01/16)
Certain spiders contain large pools of polyamine toxins, which are putative pharmacological tools awaiting further discovery. Here we present a general synthesis strategy for this class of toxins and prepare five structurally varied polyamine toxins. Elec