90991-23-4

Basic information

• Product Name: 5-(4-bromophenyl)-5-oxopentanoic acid methyl ester
• Synonyms: 5-(4-bromophenyl)-5-oxopentanoic acid methyl ester
• CAS NO: 90991-23-4
• Molecular Weight: 285.137
• Mol File: 90991-23-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 376.2±27.0 °C(Predicted)
• Density: 1.379±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-(4-bromophenyl)-5-oxopentanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-bromophenyl)-5-oxopentanoic acid methyl ester(90991-23-4)
• EPA Substance Registry System: 5-(4-bromophenyl)-5-oxopentanoic acid methyl ester(90991-23-4)

Safety Data

• Hazardous Substances Data: 90991-23-4(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 490035-81-9 methyl 5-(4-bromophenyl)pentanoate 
• 22647-95-6 5-(4-bromophenyl)pentanoic acid 
• 35333-26-7 4-bromo-δ-oxobenzenepentanoic acid 
• 108-55-4 glutaric anhydride, 
• 1501-27-5 Pentanedioic acid, monomethyl ester 
• 67-56-1 methanol 
• 16116-78-2 (4-bromophenyl)(trimethylsilyl)acetylene 
• 292638-85-8 acrylic acid methyl ester 
• 102769-20-0 5-(4-Bromo-phenyl)-5-oxo-pentanoyl chloride 

Downstream Products

• 1258204-05-5 5-(4-bromophenyl)hex-5-enoic acid 
• 1258203-98-3 (S)-6-(4-bromophenyl)-6-(iodomethyl)tetrahydro-2H-pyran-2-one 
• 229005-52-1 2-(4-methylphenyl)-N-(4-{[methyl(tetrahydro-2H-pyran-4-yl)amino]methyl}phenyl)-6,7-dihydro-5H-benzo[a][7]annulene-8-carboxamide 
• 35333-26-7 4-bromo-δ-oxobenzenepentanoic acid 
• 22647-95-6 5-(4-bromophenyl)pentanoic acid 
• 87779-78-0 3-bromo-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one 
• 102769-20-0 5-(4-Bromo-phenyl)-5-oxo-pentanoyl chloride 
• 267880-78-4 6-(4-bromo-phenyl)-piperidin-2-one 
• 1261280-41-4 5-(4-bromophenyl)hex-5-enoic acid methyl ester 
• 875479-07-5 C₁₉H₂₁BrN₂O₄S 

Relevant articles and documents

Combined Photoredox/Enzymatic C?H Benzylic Hydroxylations

Chemical transformations that install heteroatoms into C?H bonds are of significant interest because they streamline the construction of value-added small molecules. Direct C?H oxyfunctionalization, or the one step conversion of a C?H bond to a C?O bond, could be a highly enabling transformation due to the prevalence of the resulting enantioenriched alcohols in pharmaceuticals and natural products,. Here we report a single-flask photoredox/enzymatic process for direct C?H hydroxylation that proceeds with broad reactivity, chemoselectivity and enantioselectivity. This unified strategy advances general photoredox and enzymatic catalysis synergy and enables chemoenzymatic processes for powerful and selective oxidative transformations.

Base-Promoted/Gold-Catalyzed Intramolecular Highly Selective and Controllable Detosylative Cyclization

A highly selective, controllable and synthetically useful base-promoted intramolecular detosylative cyclization of bis-N-tosylhydrazones has been achieved, affording N-containing heterocycles and cyclic olefins under transition-metal-free or gold-catalyzed procedures, respectively. Moreover, an effective and practical metal-free or gold-catalyzed approach to synthesize polycyclic aromatic compounds is also reported. Basic cyclizations: A highly selective, controllable, and synthetically useful base-promoted intramolecular detosylative cyclization of bis-N-tosylhydrazones affords N-containing heterocycles and cyclic olefins under transition-metal-free or gold-catalyzed procedures, respectively. Moreover, an effective and practical metal-free or gold-catalyzed approach to synthesize polycyclic aromatic compounds is also reported.

Indium(III) chloride catalyzed conjugate addition reaction of alkynylsilanes to acrylate esters

A novel and efficient procedure for the synthesis of δ,γ- alkynyl esters by the conjugate addition of alkynylsilanes to acrylate esters in the presence of a catalytic amount of indium(III) chloride has been developed. This method provides a rapid and efficient access to substituted δ,γ-alkynyl esters.