910378-56-2

Basic information

• Product Name: C₂₈H₂₂ClF₃NO₅^(1-)*Na⁽¹⁺⁾
• Synonyms: C₂₈H₂₂ClF₃NO₅^(1-)*Na⁽¹⁺⁾
• CAS NO: 910378-56-2
• Molecular Weight: 567.924
• Mol File: 910378-56-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₂ClF₃NO₅^(1-)*Na⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₂ClF₃NO₅^(1-)*Na⁽¹⁺⁾(910378-56-2)
• EPA Substance Registry System: C₂₈H₂₂ClF₃NO₅^(1-)*Na⁽¹⁺⁾(910378-56-2)

Safety Data

• Hazardous Substances Data: 910378-56-2(Hazardous Substances Data)

Upstream product

• 668455-62-7 (2R)-2-(3-{[3-(4-chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl}phenoxy)butanoic acid 

Relevant articles and documents

NOVEL CRYSTALLINE FORMS OF ANTIDIABETIC COMPOUNDS

Novel crystalline forms of two indole compounds connected to phenoxyalkylcarboxylic acid groups are selective PPAR gamma partial agonists that are useful in the treatment of type 2 diabetes, hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. The novel crystal forms include a crystalline free acid dihydrate and crystalline free acid anhydrate of one compound and several crystalline forms of the free acid and the sodium salt of the second compound. The invention also relates to pharmaceutical compositions comprising these novel crystal forms, processes to prepare the crystal forms and their pharmaceutical compositions, and uses of the crystal forms in the treatment of type 2 diabetes and other PPAR gamma modulated diseases.