910619-58-8

Basic information

• Product Name: 5-(Dimethylamino)-3-hydroxy-2,2,4-trimethyl-3-phenylpentannitril
• Synonyms: 5-(Dimethylamino)-3-hydroxy-2,2,4-trimethyl-3-phenylpentannitril
• CAS NO: 910619-58-8
• Molecular Weight: 260.379
• Mol File: 910619-58-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(Dimethylamino)-3-hydroxy-2,2,4-trimethyl-3-phenylpentannitril(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(Dimethylamino)-3-hydroxy-2,2,4-trimethyl-3-phenylpentannitril(910619-58-8)
• EPA Substance Registry System: 5-(Dimethylamino)-3-hydroxy-2,2,4-trimethyl-3-phenylpentannitril(910619-58-8)

Safety Data

• Hazardous Substances Data: 910619-58-8(Hazardous Substances Data)

Upstream product

• 78-82-0 Isobutyronitrile 
• 91-03-2 3-dimethylamino-2-methyl-1-phenyl-propan-1-one 

Relevant articles and documents

Alkyliron- and Alkylcobalt Reagents, V.- Anticheleselective Cyanoalkylation with Cyanoalkyl Derivatives of Iron(II), Titanium(IV) and Further Transition Metals

In intermolecular competition experiments with substrate pairs which consist of a β-functionalized ketone and a normal ketone, cyanoalkyl derivatives of Fe, Ti, Cr, and Mn prefer in every case the normal ketone ("anticheleselectivity").NC-CH2Ti(OiPr)3 (4a) and NC-CH2FeCl (3a) are the best reagents for the anticheleselective transfer of the cyanomethyl group.For the anticheleselective transfer of the cyanoisopropyl group, NC-CMe2FeCl (3b) is superior to the corresponding Ti reagents.The ability of 4a as a highly anticheleselective cyanomethylating reagent has also been demonstrated with an intramolecular competition system (diketon 13).The reasons for the observed anticheleselectivity are discussed. Key Words: Organoiron compounds / Organotitanium compounds / Cyanoalkylation