91065-80-4Relevant articles and documents
Livingstone
, p. 76,78 (1962)
Benzopyranyl tetracycle compound and pharmaceutical composition having excellent anti-inflammatory effect comprising the same
-
, (2019/01/07)
The present invention relates a novel compound represented by the following Formula 3 or Formula 5, and a pharmaceutical composition having superior anti-inflammatory effect comprising the above. The above compound inhibits the translocation of HMGB1 form nucleus to cytosol, and then has remarkable effect of treating or preventing inflammatory disease, especially sepsis.
An expedient protocol for conversion of olefins to α-bromo/iodoketones using IBX and NBS/NIS
Moorthy, Jarugu Narasimha,Senapati, Kalyan,Singhal, Nidhi
experimental part, p. 2493 - 2496 (2009/08/17)
A variety of olefins have been shown to undergo conversion to the corresponding α-bromo/iodoketones when reacted with NBS/NIS and IBX in DMSO at room temperature. While the reaction is found to occur rapidly with e-rich arylolefins leading to the corresponding haloketones in 65-95% yields in 0.3-3.0 h, those containing e-withdrawing groups are found to yield diketones concomitantly, such that the latter are the exclusive products over extended duration of the reactions.