910789-99-0

Basic information

• Product Name: 4-[4-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester
• Synonyms: 4-[4-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester
• CAS NO: 910789-99-0
• Molecular Weight: 547.81
• Mol File: 910789-99-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[4-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester(910789-99-0)
• EPA Substance Registry System: 4-[4-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester(910789-99-0)

Safety Data

• Hazardous Substances Data: 910789-99-0(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 910789-89-8 4-(tert-butyl-diphenyl-silanyloxy)-3-formyl-2,2-dimethyl-butyric acid methyl ester 
• 87770-83-0 (Z)-4-((tert-butyldiphenylsilyl)oxy)but-2-en-1-ol 
• 910789-87-6 3-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-pent-4-enoic acid 
• 910789-86-5 isobutyric acid 4-(tert-butyl-diphenyl-silanyloxy)-but-2-enyl ester 
• 910789-88-7 3-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-pent-4-enoic acid methyl ester 
• 135908-33-7 methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate hydrochloride 

Relevant articles and documents

Discovery of orally active butyrolactam 11β-HSD1 inhibitors

A series of metabolically stable butyrolactam 11β-HSD1 inhibitors have been synthesized and biologically evaluated. These compounds exhibit excellent HSD1 potency and HSD2 selectivity, pharmacokinetic, and pharmacodynamic profiles.