911217-14-6

Basic information

• Product Name: [1,1'-Biphenyl]-2-amine, 4'-methyl-N-phenyl-
• CAS NO: 911217-14-6
• Molecular Formula: C19H17N
• Molecular Weight: 259.351
• Mol File: 911217-14-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [1,1'-Biphenyl]-2-amine, 4'-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Biphenyl]-2-amine, 4'-methyl-N-phenyl-(911217-14-6)
• EPA Substance Registry System: [1,1'-Biphenyl]-2-amine, 4'-methyl-N-phenyl-(911217-14-6)

Safety Data

• Hazardous Substances Data: 911217-14-6(Hazardous Substances Data)

Upstream product

• 91-40-7 2-(phenylamino)benzoic acid 
• 106-38-7 para-bromotoluene 
• 114772-53-1 2-Cyano-4'-methylbiphenyl 
• 62-53-3 aniline 

Relevant articles and documents

Biaryl synthesis via Pd-catalyzed decarboxylative coupling of aromatic carboxylates with aryl halides

A new strategy for the regiospecific construction of unsymmetrical biaryls is presented, in which easily available salts of carboxylic acids are decarboxylated in situ to give arylmetal species that serve as the nucleophilic component in a catalytic cross-coupling reaction with aryl halides. The catalyst system consists of a copper phenanthroline complex that mediates the extrusion of CO2 from aromatic carboxylates to generate arylcopper species, and a palladium complex that catalyzes the cross-coupling of these intermediates with aryl halides. This bimetallic system allows the direct coupling of various aryl, heteroaryl, or vinyl carboxylic acids with aryl or heteroaryl iodides, bromides, or chlorides at 160°C in the presence of a mild base such as potassium carbonate. The present scope and potential economic impact of the reaction are demonstrated by the synthesis of 42 biaryls, some of which are of substantial industrial relevance. Remaining challenges and future perspectives of the new transformation are discussed.

Method For Decarboxylating C-C Cross-Linking Of Carboxylic Acids With Carbon Electrophiles

The invention relates to a method for decarboxylating C—C bond formation by reacting carboxylic salts with carbon electrophiles in the presence of transition metal compounds as catalysts. The method represents a decarboxylating C—C bond formation of carboxylic acid salts with carbon electrophiles, wherein the catalyst contains two transition metals and/or transition metal compounds, from which one is present, preferably, in the oxidation step, which are different from each other by one unit, and catalyzes a radical decarboxylation which is absorbed during the second oxidation steps, which are different from each other by two units and catalyzes the two electron processes of a C—C bond formation reaction.