911319-66-9

Basic information

• Product Name: (1R,2R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-oxo-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane
• Synonyms: (1R,2R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-oxo-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane
• CAS NO: 911319-66-9
• Molecular Weight: 608.85
• Mol File: 911319-66-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-oxo-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-oxo-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane(911319-66-9)
• EPA Substance Registry System: (1R,2R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-oxo-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane(911319-66-9)

Safety Data

• Hazardous Substances Data: 911319-66-9(Hazardous Substances Data)

Upstream product

• 911319-45-4 (1R,2S,3R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-hydroxy-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane 
• 911319-65-8 (2R,3R)-2-tert-butoxycarbonylamino-3-(6-methoxyquinol-4-yl)-3-triethylsilyloxy-propanal 
• 911319-44-3 (2R,3R)-2-tert-Butoxycarbonylamino-3-(6-methoxy-quinolin-4-yl)-3-triethylsilanyloxy-propionic acid methyl ester 
• 911319-63-6 (3R,5R,6S)-3-[(R)-(6-Methoxy-quinolin-4-yl)-triethylsilanyloxy-methyl]-5,6-diphenyl-morpholin-2-one 
• 911319-43-2 (3R,5R,6S)-3-[(R)-(6-Methoxy-quinolin-4-yl)-triethylsilanyloxy-methyl]-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 911319-64-7 (2R,3R)-2-((1R,2S)-2-Hydroxy-1,2-diphenyl-ethylamino)-3-(6-methoxy-quinolin-4-yl)-3-triethylsilanyloxy-propionic acid methyl ester 
• 911319-42-1 (3R,5R,6S)-3-[(R)-Hydroxy-(6-methoxy-quinolin-4-yl)-methyl]-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 104-94-9 4-methoxy-aniline 
• 41037-26-7 6-methoxy-4-methylquinoline 
• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 
• 4363-94-4 6-methoxyquinoline-4-carbaldehyde 

Downstream Products

• 911319-46-5 (1R,2S,3S)-6-benzyloxy-2-tert-butoxycarbonylamino-3-hydroxy-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane 
• 911319-71-6 Benzoic acid (E)-4-{(2S,3S)-3-hydroxy-2-[(R)-(6-methoxy-quinolin-4-yl)-triethylsilanyloxy-methyl]-piperidin-1-yl}-but-2-enyl ester 
• 911319-51-2 (2R)-1-[(E)-4-benzoyloxy-2-butenyl]-2-[(R)-6-methoxyquinol-4-yl-triethylsilyloxy]methyl-3-oxo-piperidine 
• 911319-67-0 (1R,2S,3S)-6-benzyloxy-3-acetoxy-2-tert-butoxycarbonylamino-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane 
• 911319-72-7 (R)-1-((E)-4-Benzoyloxy-but-2-enyl)-2-[(R)-(6-methoxy-quinolin-4-yl)-triethylsilanyloxy-methyl]-3-oxo-piperidine-4-carboxylic acid methyl ester 
• 911319-56-7 Benzoic acid (E)-4-{(R)-6-[(R)-(6-methoxy-quinolin-4-yl)-triethylsilanyloxy-methyl]-5-trimethylsilanyloxy-3,6-dihydro-2H-pyridin-1-yl}-but-2-enyl ester 
• 911319-50-1 (2S,3S)-1-[(E)-4-benzoyloxy-2-butenyl]-2-[(R)-6-methoxyquinol-4-yl-triethylsilyloxy]methyl-3-trimethylsilyloxy-piperidine 

Relevant articles and documents

Synthetic studies on quinine: Quinuclidine construction via a ketone enolate regio- and diastereoselective Pd-mediated allylic alkylation

7-Hydroxy-quinine was synthesized by an asymmetric aldol reaction that establishes the C8 and C9 stereochemistry, followed by construction of the 3-vinyl-quinuclidine azabicyclo[2.2.2]octane by C3-C4 ring closure using an intramolecular palladium-mediated