911370-66-6Relevant articles and documents
Design and development of arrayable syntheses to accelerate SAR studies of pyridopyrimidinone and pyrimidopyrimidinone
Wan, Zehong,Yan, Hongxing,Hall, Ralph F.,Lin, Xichen,Livia, Stefano,Respondek, Tomasz,Widdowson, Katherine L.,Zhu, Chongjie,Callahan, James F.
experimental part, p. 370 - 372 (2009/04/19)
Chemoselectivity of chlorine versus methylthio (-SCH3), methylsulfinyl (-SOCH3), or methylsulfonyl [-S(O)2CH3] in either functionalization or substitution of pyridopyrimidinone and pyrimidopyrimidinone was studi
NOVEL COMPOUNDS
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, (2008/06/13)
Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds, and 1,5,7-trisubstituted-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2-(1H)-one compounds and compositions, and their use in therapy as CSBP/RK/p38 kinase inhibitors.
PROCESS FOR PREPARING PYRIDO[2,3-D]PYRIMIDIN-7-ONE AND 3,4-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-2(1H)-ONE DERIVATIVES
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Page/Page column 86, (2008/06/13)
The present invention is directed to a novel method of preparing of 2,4,8- trisubstituted pyrido[2,3-d]pyrimidin-7-one pharmacophores of Formula (II) or (Ha) wherein GHs CH2 Or NH: G2 is CH or nitrogen; Rx is chloro, bromo, iodo, or O-S(O)