911470-50-3

Basic information

• Product Name: (Z)-(R)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-pent-2-enoic acid methyl ester
• CAS NO: 911470-50-3
• Molecular Weight: 378.425
• Mol File: 911470-50-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-(R)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-pent-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(R)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-pent-2-enoic acid methyl ester(911470-50-3)
• EPA Substance Registry System: (Z)-(R)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-pent-2-enoic acid methyl ester(911470-50-3)

Safety Data

• Hazardous Substances Data: 911470-50-3(Hazardous Substances Data)

Upstream product

• 146553-06-2 tert-butyl N-[(1R)-2-[methoxy(methyl)amino]-1-methyl-2-oxo-ethyl]carbamate 
• 3744-87-4 Boc-(R)-Ala 
• 100945-15-1 N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester 
• 82353-56-8 (2R)-2-N-t-butoxycarbonyl-aminopropanal 

Downstream Products

• 911470-83-2 [(1S,3R)-3-(4-Chloro-benzylamino)-1-(piperidine-1-carbonyl)-butyl]-carbamic acid benzyl ester 

Relevant articles and documents

Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines

In this paper, we report the synthesis of diastereomerically pure N-(4-substituted-2,4-diaminobutanoyl)piperidines. These compounds were prepared to investigate the influence of the 4-substitution on the dipeptidyl peptidase II (DPP II) activity and selectivity of the parent N-(2,4-diaminobutanoyl)piperidine. The (4S)-methyl compound showed subnanomolar inhibition, comparable with the parent compound. The (4R)-methyl group or bigger substituents decreased the activity.