911676-49-8

Basic information

• Product Name: 2-[(1S,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole
• Synonyms: 2-[(1S,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole
• CAS NO: 911676-49-8
• Molecular Weight: 409.528
• Mol File: 911676-49-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(1S,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1S,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole(911676-49-8)
• EPA Substance Registry System: 2-[(1S,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole(911676-49-8)

Safety Data

• Hazardous Substances Data: 911676-49-8(Hazardous Substances Data)

Upstream product

• 171046-58-5 (+)-(5S)-1-(4,5-diphenyloxazol-2-yl)-5-(3-methoxybenzyl)cyclopentene 
• 171046-88-1 (S)-5-(3-Methoxy-benzyl)-cyclopent-1-enecarbonyl chloride 
• 171046-49-4 (-)-5(S)-(3-methoxybenzyl)-1-cyclopentenecarboxylic acid 
• 171046-47-2 (-)-ethyl 5(S)-(3-methoxybenzyl)-1-cyclopentencarboxylate 
• 143168-16-5 ethyl (R)-5-acetoxycyclopent-1-enecarboxylate 
• 824-98-6 m-methoxybenzyl chloride 

Downstream Products

• 911676-51-2 3-[(1S,2S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclopentylmethyl]-phenol 

Relevant articles and documents

Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: Orally active prostacyclin mimetics. Part 6

The synthesis and biological activity of novel derivatives of our previously reported IP receptor agonist FR181157 is described. SAR studies to replace the cyclohexene-linker of FR181157 led to the discovery of compound 1i (FR207845) as a potent non-prost