911697-23-9

Basic information

• Product Name: (R)-7-Benzyl-2,4-dioxo-1,3,7-triaza-spiro[4.4]nonane-8-carboxylic acid ethyl ester
• CAS NO: 911697-23-9
• Molecular Weight: 317.345
• Mol File: 911697-23-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-7-Benzyl-2,4-dioxo-1,3,7-triaza-spiro[4.4]nonane-8-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-7-Benzyl-2,4-dioxo-1,3,7-triaza-spiro[4.4]nonane-8-carboxylic acid ethyl ester(911697-23-9)
• EPA Substance Registry System: (R)-7-Benzyl-2,4-dioxo-1,3,7-triaza-spiro[4.4]nonane-8-carboxylic acid ethyl ester(911697-23-9)

Safety Data

• Hazardous Substances Data: 911697-23-9(Hazardous Substances Data)

Upstream product

• 151-50-8 potassium cyanide 
• 506-87-6 ammonium carbonate 
• 171192-74-8 (2R)-ethyl N¹-benzyl-4-oxopyrrolidine-2-carboxylate 
• 100-39-0 benzyl bromide 
• 2584-71-6 cis-hydroxy-D-proline 
• 171192-72-6 (2R,4R)-ethyl N¹-benzyl-4-hydroxypyrrolidine-2-carboxylate 
• 1111-78-0 ammonium carbamate 

Downstream Products

• 174266-80-9 diethyl (2R,4R)-1-benzyl-4-aminopyrrolidine-2,4-dicarboxylate 
• 178963-35-4 (2R,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid diethyl ester 
• 911697-24-0 (2R,4S)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 911697-28-4 (2R,4S)-1-Benzyl-4-tert-butoxycarbonylamino-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 911697-25-1 (2R,4R)-4-amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 238753-26-9 (2R,4R)-1-benzyl-4-tert-butoxycarbonylamino-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 179030-55-8 (2R,4S)-1-Benzyl-4-tert-butoxycarbonylamino-pyrrolidine-2,4-dicarboxylic acid diethyl ester 
• 174266-81-0 (2R,4R) diethyl-1-benzyl-4-(tert-butyloxycarbonylamino) pyrrolidine-2,4-dicarboxylate 
• 171336-79-1 (2R,4S)-4-amino-4-carboxyproline 
• 169209-63-6 (2R,4R)-4-amino-4-carboxyproline 

Relevant articles and documents

Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): Identification of a new group III metabotropic glutamate receptor selective agonist

A new family of mGlu receptor orthosteric ligands called APTCs was designed and synthesized using a parallel chemistry approach. Amongst 65 molecules tested on mGlu4, mGlu6 and mGlu8 subtypes, (2S,4S)-4-amino-1-[(E)-3-carboxyacryloyl]pyrrolidine-2,4-dicar