91190-73-7

Basic information

• Product Name: o-(Hydroxymethyl)-N,N-dimethylbenzenesulfonamide
• Synonyms: o-(Hydroxymethyl)-N,N-dimethylbenzenesulfonamide
• CAS NO: 91190-73-7
• Molecular Weight: 215.273
• Mol File: 91190-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: o-(Hydroxymethyl)-N,N-dimethylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: o-(Hydroxymethyl)-N,N-dimethylbenzenesulfonamide(91190-73-7)
• EPA Substance Registry System: o-(Hydroxymethyl)-N,N-dimethylbenzenesulfonamide(91190-73-7)

Safety Data

• Hazardous Substances Data: 91190-73-7(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 14417-01-7 N,N-dimethylbenzenesulfonamide 

Downstream Products

• 112320-51-1 o-2-propenyl-N-methylbenzenesulfonamide 

Relevant articles and documents

Intramolecular Nucleophilic Catalysis by the Neighboring Hydroxyl Group in Acid-Catalyzed Benzenesulfonamide Hydrolysis

The reactivity towards the neighboring hydroxyl group of two N,N-dialkylbenzenesulfonamide systems 1 and 2 is extraordinarily sensitive to structure.In the presence of o-CH2OH, the SO2NMe2 group is stable almost indefinitely in 1 M HCl, whereas the corresponding compound with o-CMe2OH cyclizes to the sultone under the same conditions with a half-life of around 20 min.When the sulfonamide group is constrained in a five-membered ring its cleavage must be followed by the stopped-flow technique.These very large variations in reactivity are interpreted primarily in termsof ground-state strain, which is partially relieved in the transition state for cyclization.