912296-93-6

Basic information

• Product Name: 2,2-dichloro-N-[1-hydroxymethyl-2-methoxy-2-(4-nitrophenyl)-ethyl]-acetamide
• Synonyms: 2,2-dichloro-N-[1-hydroxymethyl-2-methoxy-2-(4-nitrophenyl)-ethyl]-acetamide
• CAS NO: 912296-93-6
• Molecular Weight: 337.16
• Mol File: 912296-93-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-dichloro-N-[1-hydroxymethyl-2-methoxy-2-(4-nitrophenyl)-ethyl]-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dichloro-N-[1-hydroxymethyl-2-methoxy-2-(4-nitrophenyl)-ethyl]-acetamide(912296-93-6)
• EPA Substance Registry System: 2,2-dichloro-N-[1-hydroxymethyl-2-methoxy-2-(4-nitrophenyl)-ethyl]-acetamide(912296-93-6)

Safety Data

• Hazardous Substances Data: 912296-93-6(Hazardous Substances Data)

Upstream product

• 116-54-1 dichloroacetic acid methyl ester 
• 99170-59-9 syn-(2R,3R)-[2-amino-3-methoxy-3-(4-nitrophenyl)-1-propanol] 

Downstream Products

• 56-75-7 chloramphenicol 

Relevant articles and documents

Stereoselective syntheses of (-)-chloramphenicol and (+)-thiamphenicol

Chloramphenicol and thiamphenicol have been enantioselectively synthesized using an asymmetric halohydrin reaction as a key step. In particular, halomethoxylation reaction was used, where O-methyl functions as a hydroxyl protecting group and eliminates an additional protection step.