91247-72-2

Basic information

• Product Name: 1-propyl (4-methoxyphenyl)carbamate
• Synonyms: 1-propyl (4-methoxyphenyl)carbamate
• CAS NO: 91247-72-2
• Molecular Weight: 209.245
• Mol File: 91247-72-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-propyl (4-methoxyphenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-propyl (4-methoxyphenyl)carbamate(91247-72-2)
• EPA Substance Registry System: 1-propyl (4-methoxyphenyl)carbamate(91247-72-2)

Safety Data

• Hazardous Substances Data: 91247-72-2(Hazardous Substances Data)

Upstream product

• 71-23-8 propan-1-ol 
• 590-28-3 potassium cyanate 
• 25940-64-1 2,4,6-tris(4-methoxyphenoxy)-1,3,5-triazine 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 
• 540-54-5 1-Chloropropane 
• 124-38-9 carbon dioxide 
• 104-94-9 4-methoxy-aniline 
• 106-94-5 propyl bromide 
• 627-12-3 1-propyl carbamate 
• 1227-44-7 N,N'-bis(4-methoxyphenyl)urea 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 5416-93-3 4-Methoxyphenyl isocyanate 

Relevant articles and documents

Carbon dioxide utilization in the efficient synthesis of carbamates by deep eutectic solvents (DES) as green and attractive solvent/catalyst systems

A green and eco-friendly solvent/catalyst system based on a deep eutectic solvent (DES) was devised and developed for the simple synthesis of carbamates through three-component coupling of amines, alkyl halides and carbon dioxide (CO2). It was found that choline chloride:zinc(ii) chloride ([ChCl][ZnCl2]2) was very proficient and effective for the activation and utilization of CO2 in carbamate formation reactions from a wide scope of amines. Surprisingly, this strategy provides the desired carbamates under atmospheric CO2 pressure at room temperature. In particular, both aromatic and aliphatic amines were effective and demonstrated excellent yields. Besides, the [ChCl][ZnCl2]2 exhibited very high stability and also could be reused for at least five consecutive cycles without any significant loss of activity. It is worth noting that this is the first solvent/catalyst system which can be recycled successfully from the reaction mixture.

A Fe3O4?SiO2/Schiff Base/Pd Complex as an Efficient Heterogeneous and Recyclable Nanocatalyst for One-Pot Domino Synthesis of Carbamates and Unsymmetrical Ureas

A palladium-catalyzed domino method for the direct synthesis of carbamates and ureas has been developed by using readily available and economical starting materials (aryl halide, carbon monoxide, sodium azide, amines and alcohols) in a one-pot approach. The domino process underwent carbonylation, Curtius rearrangement, and nucleophilic addition. This protocol provides a step-economical and highly efficient reaction to access the wide range of valuable carbamates, symmetrical and unsymmetrical ureas with high yields under remarkable mild reaction conditions that are important factors in pharmaceutical science, biochemistry and agricultural industries. Furthermore, the magnetically recoverable nanocatalyst (Fe3O4?SiO2/Pd(II)) can be conveniently and swiftly recycled using external magnet and reused at least for seven times without noticeable loss of its catalytic activity.

Ureas as safe carbonyl sources for the synthesis of carbamates with deep eutectic solvents (DESs) as efficient and recyclable solvent/catalyst systems

A simple, efficient and eco-friendly one-pot synthesis of primary, N-mono- and N-disubstituted carbamates is developed from ureas. The corresponding carbamates were produced at 120 °C, within 18 h, and in the presence of a deep eutectic solvent as a recyclable catalytic system. The catalyst can be reused for several runs without any reduction in its activity. To demonstrate the utility of this approach, a wide variety of alcohols and phenols were studied to find a vast range of carbamate derivatives in moderate to high yields.