912480-01-4Relevant articles and documents
A novel and efficient method for the synthesis of 1,2-diazetidines
Miao, Wei,Xu, Weiliang,Zhang, Zhiliu,Ma, Rujian,Chen, Shu-Hui,Li, Ge
, p. 6835 - 6837 (2006)
A novel and efficient method has been developed for the preparation of racemic or optically pure 1,2-diazetidine from 1-(1-hydroxy-propan-2-yl)hydrazine-1,2-dicarboxylate under very mild conditions with excellent yield.
Asymmetric α-amination of aldehydes catalyzed by PS-diphenylprolinol silyl ethers: Remediation of catalyst deactivation for continuous flow operation
Fan, Xinyuan,Sayalero, Sonia,Pericas, Miquel A.
supporting information, p. 2971 - 2976,6 (2012/12/13)
Polystyrene (PS)-supported diphenylprolinol silyl ethers have been developed as highly active catalysts for the enantioselective α-amination of aldehydes. Understanding the mechanism of catalyst deactivation has led to the development of reaction conditions notably extending catalyst life in repeated recycling (10 cycles; accumulated TON of 480) and has allowed the implementation of a continuous flow α-amination process (6 min residence time, 8 h operation). Copyright
An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline
Talluri, Siva Kumar,Sudalai, Arumugam
, p. 9758 - 9763 (2008/02/12)
An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.
