912771-38-1

Basic information

• Product Name: 2-(3-METHOXY-PHENYL)-PYRAZINE
• Synonyms: 2-(3-METHOXY-PHENYL)-PYRAZINE
• CAS NO: 912771-38-1
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.21
• Mol File: 912771-38-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 309.2°C at 760 mmHg
• Flash Point: 106.1°C
• Appearance: /
• Density: 1.127g/cm³
• Vapor Pressure: 0.00118mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: 2-(3-METHOXY-PHENYL)-PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-METHOXY-PHENYL)-PYRAZINE(912771-38-1)
• EPA Substance Registry System: 2-(3-METHOXY-PHENYL)-PYRAZINE(912771-38-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 912771-38-1(Hazardous Substances Data)

Usage

Pyrazine derivative

A type of organic compound containing a six-membered ring with two nitrogen atoms in the 1,4 position This describes the basic structure of the compound, which is derived from pyrazine.

Phenyl group attached to the 2-position

A benzene ring connected to the pyrazine ring at the second carbon atom This detail specifies the location of the phenyl group on the pyrazine ring.

Methoxy group attached to the 3-position

An oxygen and a methyl group (-OCH3) connected to the pyrazine ring at the third carbon atom This detail specifies the location and type of the methoxy group on the pyrazine ring.

Flavoring agent

Commonly used in the food and beverage industry This property highlights the compound's application in adding flavor and aroma to various products.

Characteristic odor and taste

The reason for its use as a flavoring agent This describes the sensory properties of the compound that make it suitable for use in the food and beverage industry.

Use in perfumes and fragrances

Utilized in the manufacturing of scented products This property indicates another application of the compound, contributing to its aroma.

Pharmaceutical industry

Potential medicinal properties This suggests that the compound may have therapeutic uses or effects, making it of interest to the pharmaceutical sector.

InChI:InChI=1/C11H10N2O/c1-14-10-4-2-3-9(7-10)11-8-12-5-6-13-11/h2-8H,1H3

Upstream product

• 290-37-9 1,4-pyrazine 
• 766-85-8 3-methoxy-1-iodobenzene 
• 10365-98-7 3-methoxyphenylboronic acid 
• 768-70-7 1-ethynyl-3-methoxybenzene 
• 107-15-3 ethylenediamine 
• 14508-49-7 2-chloropyrazin 
• 30882-41-8 pyrazine hydrochloride 

Relevant articles and documents

NaH-mediated direct C-H arylation in the presence of 1,10-phenanthroline

Transition-metal-free coupling of haloarenes with unactivated arenes has been developed in the presence of NaH and 1,10-phenanthroline. Various haloarenes bearing methyl, methoxy, halogen (fluoride, chloride, and bromide), cyano, trifluoromethyl, ester, and amide groups can be cross-coupled with unactivated arenes, or heteroarenes in this reaction.

Graphene oxide-phenalenyl composite: transition metal-free recyclable and catalytic C-H functionalization

An efficient route towards a heterogeneous transition metal-free catalytic C-H functionalization using a covalently linked graphene oxide-phenalenyl conjugate is described herein (28 examples, which include a core of some biologically relevant biaryl and hetero-biaryls). It is an environmentally benign, economical and heterogeneous platform, whose catalytic activity can easily be regenerated through a simple washing-drying technique and the catalytic activity can be retained even after 10 cycles.

Iodine-mediated oxidative annulation for one-pot synthesis of pyrazines and quinoxalines using a multipathway coupled domino strategy

An efficient iodine-mediated oxidative annulation of aryl acetylenes-arylethenes-aromatic ketones with 1,2-diamines for the synthesis of pyrazines and regioselective synthesis of quinoxalines is presented. A multipathway coupled domino approach has been developed for the one-pot synthesis of 1,4-diazines with high functional group compatibility.