913258-78-3Relevant articles and documents
Potential anticancer drugs, 4 - Glycosyl glycerol derivatives as drug carrier system. Stereoselective synthesis of epoxyalkyl N-acyl-β-D-glucopyranosides and their reactivity with nucleophiles
Vega-Perez, Jose M.,Candela, Jose I.,Romero, Isidora,Blanco, Eugenia,Iglesias-Guerra, Fernando
, p. 3949 - 3956 (2007/10/03)
The synthesis of alkenyl 2-acylamino-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosides from N-acetyl-D-glucosamine is described. The oxidation of alkenyl glycosides with m-CPBA gives the corresponding oxiranes in good yields, and with high stereoselectivity. Analogues of glycosyl glycerol derivatives, which can be used as drug carriers, were obtained by various ring-opening reactions with different nitrogen, sulfur, and carbon nucleophiles.