91341-03-6

Basic information

• Product Name: 2-cyano-2-methyl-1,5-pentanedioic acid bis(ethyl ester)
• Synonyms: 2-cyano-2-methyl-1,5-pentanedioic acid bis(ethyl ester)
• CAS NO: 91341-03-6
• Molecular Weight: 227.26
• Mol File: 91341-03-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-cyano-2-methyl-1,5-pentanedioic acid bis(ethyl ester)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-2-methyl-1,5-pentanedioic acid bis(ethyl ester)(91341-03-6)
• EPA Substance Registry System: 2-cyano-2-methyl-1,5-pentanedioic acid bis(ethyl ester)(91341-03-6)

Safety Data

• Hazardous Substances Data: 91341-03-6(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 107-13-1 acrylonitrile 
• 140-88-5 ethyl acrylate 

Relevant articles and documents

Cobalt Carbonyl Mediated Michael Addition: Direct Synthesis of Esters Containing Other Functional Groups from Activated Olefins

Hydrocarbalkoxylation of acrylonitrile with stoichiometric amounts of alcohols in the presence of catalytic amounts of Co2(CO)8 and pyridine bases leads to 2,4-dicyano-2-methylbutanoic acid esters.The yield of these Michael adducts shows a maximum as a function of the pyridine/cobalt ratio.Analogues reactions using equimolar amounts of alcohol, acrylonitrile, and an other activated olefin result in products with at least three different functional groups.Acrylonitrile with pyH gives (1-cyanoethyl)cobalt tetracarbonyl, which is proposed to be the key intermediate of the hydrocarbalkoxylation.This complex may be deprotonated to a "Michael donor" anion, i.e. the Michael adducts are most probably formed in a cobalt-mediated way.The above catalytic system promoted also the Michael addition of some C-H acids to activated olefins under atmospheric conditions.