913715-42-1Relevant articles and documents
Concise synthesis of trans- and cis-3,4-disubstituted piperidines based on regio- and stereoselective allylation of cyclopentenyl esters
Igarashi, Junji,Ishiwata, Hiroyuki,Kobayashi, Yuichi
, p. 8065 - 8068 (2004)
3,4-Disubstituted piperidines were synthesized through anti S N2′ allylation of 4-substituted 2-cyclopentenyl esters with reagents based on RMgX and CuX, thus allowing equal access to both trans- and cis-isomers. As an application, the paroxeti