913720-11-3Relevant articles and documents
A convenient cyclopropanation process of oxindoles via bromoethylsulfonium salt
Qin, Hui,Miao, Yuanyuan,Zhang, Ke,Xu, Jian,Sun, Haopeng,Liu, Wenyuan,Feng, Feng,Qu, Wei
, p. 6809 - 6814 (2018/10/20)
A practical convenient conversion of oxindoles into the corresponding spirocyclopropyl oxindoles is achieved efficiently using bromoethylsulfonium salt, which is easily prepared on a large scale and is stable crystalline. This reaction of bromoethylsulfonium salt with different substituted unprotected oxindoles proceeded under mild condition and provided moderate yields.
Process for the preparation of indolin-2-one derivatives useful as PR modulators
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Page/Page column 19-20, (2010/11/30)
Processes for dialkylating indolinones, specifically indolin-2-ones are provided. The processes for dialkylating an indolin-2-one include performing the dialkylation in the presence of at least 2 equivalents of a first base, a second base containing at le
Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles
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Page/Page column 21-22, (2008/06/13)
Methods for preparing oxindole and thio-oxindole compounds are provided, which compounds are useful as precursors to useful pharmaceutical compounds. Specifically provided are methods for preparing 5-pyrrole-3,3-oxindole compounds and 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile. Also provided are methods for preparing iminobenzo[b]thiophene and benzo[b]thiophenone compounds.
