913733-27-4

Basic information

• Product Name: Fmoc-N-Me-Arg(pbf)-OH
• Synonyms: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid;Fmoc-N-Me-L-Arg(Pbf)-OH;Nα-Fmoc-Nα-methyl-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sufonyl)-L-arginine≥ 99% (HPLC);Fmoc-N-Me-Arg(pbf)-OH;N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N2-methyl-L-ornithine;(9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-Arg(pbf)-OH;Fmoc-N-Me-Arg(Pbf)-OH N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N2-methyl-L-ornithine;FMOC-MEARG(PBF)-OH
• CAS NO: 913733-27-4
• Molecular Formula: C35H42N4O7S
• Molecular Weight: 662.79558
• Product Categories: amino acids
• Mol File: 913733-27-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 817.5±75.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 3.85±0.21(Predicted)
• CAS DataBase Reference: Fmoc-N-Me-Arg(pbf)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Fmoc-N-Me-Arg(pbf)-OH(913733-27-4)
• EPA Substance Registry System: Fmoc-N-Me-Arg(pbf)-OH(913733-27-4)

Safety Data

• Hazardous Substances Data: 913733-27-4(Hazardous Substances Data)

Usage

Description

Fmoc-N-Me-Arg(pbf)-OH, with the CAS number 913733-27-4, is a peptide characterized by its white powder form. It is known for its predicted boiling point of 817.5±75.0 °C and a density of 1.34±0.1 g/cm3. Due to its chemical properties, it requires storage in a sealed, dry, and cold environment at -20℃ to maintain its stability and integrity.

Uses

Used in Pharmaceutical Industry:
Fmoc-N-Me-Arg(pbf)-OH is utilized as a key component in the synthesis of tetrapeptide aldehyde inhibitors. These inhibitors are specifically designed to target and inhibit the activity of the dengue virus NS3 protease. By doing so, they play a crucial role in the development of potential antiviral therapies against dengue fever, a mosquito-borne tropical disease caused by the dengue virus.
In the context of drug development, Fmoc-N-Me-Arg(pbf)-OH serves as a building block for creating molecules that can effectively combat viral replication and pathogenesis, thereby contributing to the advancement of treatments for dengue virus infections.