91374-24-2 Usage
Description
Ethyl 3-[2-[2-(dipropylamino)ethyl]-6-nitrophenyl]-2-oxopropanoate is a chemical compound that is an impurity of Ropinirol (R641000), an antiparkinsonian agent and a selective dopamine D2-receptor agonist.
Uses
Used in Pharmaceutical Industry:
Ethyl 3-[2-[2-(dipropylamino)ethyl]-6-nitrophenyl]-2-oxopropanoate is used as an impurity in the production of Ropinirol, an antiparkinsonian agent. It is important to monitor and control the levels of this impurity to ensure the safety and efficacy of the drug.
Check Digit Verification of cas no
The CAS Registry Mumber 91374-24-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,3,7 and 4 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 91374-24:
(7*9)+(6*1)+(5*3)+(4*7)+(3*4)+(2*2)+(1*4)=132
132 % 10 = 2
So 91374-24-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H28N2O5/c1-4-11-20(12-5-2)13-10-15-8-7-9-17(21(24)25)16(15)14-18(22)19(23)26-6-3/h7-9H,4-6,10-14H2,1-3H3
91374-24-2Relevant articles and documents
PROCESS FOR THE PREPARATION OF ROPINIROLE AND SALTS THEREOF
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Page/Page column 6-7, (2011/07/07)
The present invention relates to an improved process for the preparation of Ropinirole and pharmaceutical acceptable salts or derivatives thereof, in particular to a process for large scale production of Ropinirole and salts thereof in high yield and high purity and pharmaceutical preparations containing said compounds.
Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones
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, (2008/06/13)
A series of pharmaceutical compositions which contain 4-aminoalkyl-2(3H)-indolones has been demonstrated to have D2 -agonist activity useful for treating congestive heart failure and hypertension. A representative ingredient of the compositions is 4-di-n-propylaminoethyl-2(3H)-indolone or a salt thereof.
