91417-06-0Relevant articles and documents
Reaction of 1-Alkyl-3,4-dihydroisoquinolines with 4-Nitrobenzoyl Cyanide and Diketene
Sakamoto, Masanori,Akimoto, Takashi,Akiyama, Yasunobu,Fukutomi, Kyoko,Ishii, Keitaro
, p. 1170 - 1173 (2007/10/02)
The reactions of 1-alkyl-3,4-dihydroisoquinolines (4a-d) with 4-nitrobenzoyl cyanide (2) gave the indolizine derivatives 5a-c and 6d, respectively.Compounds 4a and 4b also reacted with diketene (8) to give the quinolizinone derivatives 9a, b, respectively.Keywords enamine-imine prototropy; 1-alkyl-3,4-dihydroisoquinoline; 4-nitrobenzoyl cyanide; diketene; cyclization