91418-45-0

Basic information

• Product Name: 3-(4-hydroxy-3-methoxybenzylidene)pentane-2,4-dione
• CAS NO: 91418-45-0
• Molecular Formula: C₁₃H₁₄O₄
• Molecular Weight: 234.2479
• Mol File: 91418-45-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 443.3°C at 760 mmHg
• Flash Point: 171.2°C
• Density: 1.192g/cm³
• Vapor Pressure: 1.8E-08mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: 3-(4-hydroxy-3-methoxybenzylidene)pentane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-hydroxy-3-methoxybenzylidene)pentane-2,4-dione(91418-45-0)
• EPA Substance Registry System: 3-(4-hydroxy-3-methoxybenzylidene)pentane-2,4-dione(91418-45-0)

Safety Data

• Hazardous Substances Data: 91418-45-0(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 123-54-6 acetylacetone 

Downstream Products

• 916912-25-9 ethyl 5-acetyl-4-(4-hydroxy-3-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylate 
• 10354-31-1 4-(4-hydroxy-3-methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 30881-23-3 3-(4-hydroxy-3-methoxybenzyl)pentane-2,4-dione 

Relevant articles and documents

Role of Knoevenagel condensate pyrazolone derivative Schiff base ligated transition metal complexes in biological assay and cytotoxic efficacy

A new bioessential Knoevenagel condensate Schiff base ligand (L) was synthesized by the reaction of 3-(4-hydroxy-3-methoxybenzyl)pentane-2,4-dione and 4-aminoantipyrine. The ligand forms monomeric divalent transition metal complexes (1–4) which were chara

4 - arylmethyl curcumin analogs as Hsp90 inhibitors

The invention discloses application of a 4-arylmethyl curcumin analogues serving as an Hsp90 inhibitor. The 4-arylmethyl curcumin analog in serving as Hsp90 inhibitor has a structural formula as shown in the specification, wherein Ar is aromatic ring or a

Synthesis and evaluation of 4-arylmethyl curcumin analgues as potent Hsp90 inhibitors

Hsp90 is a potential target for the treatment of cancer. Curcumin is a natural product used to prevent and treat cancer. 4-(4-Hydroxy-3-methoxybenzyl) curcumin (C086), a 4-arylmethyl curcumin analogue, showed lead-like properties. Western blot analyses an