91421-74-8

Basic information

• Product Name: 5H-Pyrano[3,2-c]quinolin-5-one, 2,3,4,6-tetrahydro-2,2,6-trimethyl-
• CAS NO: 91421-74-8
• Molecular Formula: C15H17NO2
• Mol File: 91421-74-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5H-Pyrano[3,2-c]quinolin-5-one, 2,3,4,6-tetrahydro-2,2,6-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Pyrano[3,2-c]quinolin-5-one, 2,3,4,6-tetrahydro-2,2,6-trimethyl-(91421-74-8)
• EPA Substance Registry System: 5H-Pyrano[3,2-c]quinolin-5-one, 2,3,4,6-tetrahydro-2,2,6-trimethyl-(91421-74-8)

Safety Data

• Hazardous Substances Data: 91421-74-8(Hazardous Substances Data)

Upstream product

• 1677-46-9 4-hydroxy-1-methyl-2(1H)-quinolone 
• 78-79-5 isoprene 
• 109573-22-0 4-hydroxy-N-methyl-3-(3-methylbut-3-enyl)quinolin-2(1H)-one 
• 109573-28-6 4-hydroxy-3-(3-hydroxy-3-methylbutyl)-N-methylquinolin-2(1H)-one 
• 14872-56-1 5-isopropyl-2-oxo-tetrahydro-furan-3-carboxylic acid ethyl ester 
• 100-61-8 N-methylaniline 

Downstream Products

• 50333-13-6 N-methylflindersine 

Relevant articles and documents

Isoprene: A Promising Coupling Partner in C-H Functionalizations

Five-carbon dimethylallyl units, such as prenyl and reverse-prenyl, are widely distributed in natural indole alkaloids and terpenoids. In conventional methodologies, these valuable motifs are often derived from substrates bearing leaving groups, but these

A NEW APPROACH TO HEMITERPENOID TRICYCLIC QUINOLONES. SYNTHESIS OF N-METHYLFLINDERSINE, KHAPLOPHOLINE AND OTHER STRUCTURALLY SIMILAR ALKALOIDS

A new and general synthesis of tricyclic quinolone alkaloids is described which, by cyclization of 3-butenyl-4-hydroxyquinolones promoted by mercury(II) ion or by formic acid, affords pyranoquinolones and pyranoquinolones, respectively, with regio- and site-selectivity better than those obtained employing known methodologies. 3-Butenyl-4-hydroxyquinolones have been reacted with mercury(II) acetate to give, after work-up, the corresponding 2-(chloromercurymethyl)pyranoquinolones, which have been reductively demercurated with sodium borohydride and then dehydrogenated by treatment with DDQ.Alternatively, from the same starting compounds the "linear" isomers are obtained by formic acid-promoted cyclization.N-Methylflindersine, khaplofoline and other structurally similar alkaloids have been obtained.