914358-45-5

Basic information

• Product Name: syn-2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)-acetic acid
• CAS NO: 914358-45-5
• Molecular Weight: 229.216
• Mol File: 914358-45-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: syn-2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: syn-2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)-acetic acid(914358-45-5)
• EPA Substance Registry System: syn-2-(2-aminothiazol-4-yl)-2-(methylcarbonyloxyimino)-acetic acid(914358-45-5)

Safety Data

• Hazardous Substances Data: 914358-45-5(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 120570-48-1 syn-2-(2-aminothiazol-4-yl)-2-(hydroxyimino)-acetic acid 

Relevant articles and documents

Preparation method of aminothiazole acetyloxime acid with controllable particle size

The invention relates to a preparation method of aminothiazole acetyloxime acid with a controllable particle size, and belongs to the technical field of chemical pharmacy. The preparation method comprises the following steps: ahydrolysis step: hydrolyzing ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate serving as a raw material to generate a compound 1; an acylation step: dropwisely adding an acylating agent into the system to perform acylation reaction to obtain a compound 2; and a crystallization step: adding activated carbon into the reaction system for decolorization, then dropwise adding an acidic solution into the system at different temperatures to control the pH value of the system, and after the solid is separated out, carrying out centrifugal drying to obtain a compound 3 with controllable particle size. According to the method, by controlling different acid liquor adding temperatures, the particle size of the prepared aminothiazole acetyloxime acid is controllable; and the technological process is simple to operate and suitable for industrial production.