914360-11-5

Basic information

• Product Name: (2R)-4-(8-mentholyl)-2-methyl-morpholine
• Synonyms: (2R)-4-(8-mentholyl)-2-methyl-morpholine
• CAS NO: 914360-11-5
• Molecular Weight: 255.401
• Mol File: 914360-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-4-(8-mentholyl)-2-methyl-morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-4-(8-mentholyl)-2-methyl-morpholine(914360-11-5)
• EPA Substance Registry System: (2R)-4-(8-mentholyl)-2-methyl-morpholine(914360-11-5)

Safety Data

• Hazardous Substances Data: 914360-11-5(Hazardous Substances Data)

Upstream product

• 454251-71-9 (2S,4aS,7R,8aR)-N-allyl-2-hydroxymethyl-4,4,7-trimethyl-octahydro-1,3-benzoxazine 
• 914359-85-6 (3S,6aS,9R,10aR,11aS)-3-phenylselenenylmethyl-6,6,9-trimethyl-decahydro-3H,7H-[1,4]oxazino[3,4-b][1,3]benzoxazine 
• 914359-99-2 (3R,6aS,9R,10aR,11aS)-3,6,6,9-tetramethyl-decahydro-3H,7H-[1,4]oxazino[3,4-b][1,3]benzoxazine 

Downstream Products

• 790184-33-7 (2R)-2-methyl-morpholine 

Relevant articles and documents

Diastereoselective synthesis of enantiopure morphelines by electrophilic selenium-induced 6-exo cyclizations on chiral 3-allyl-2-hydroxymethylperhydro-1, 3-benzoxazine derivatives

Enantiopure morpholine derivatives have been prepared by selenocyclofunctionalization of chiral 3-allyl-2-hydroxymethyl-substituted perhydro-1,3-benzoxazine derivatives. The cyclization occurs in high yields and diastereoselection, although the temperature of the reaction and the structure of the substituent at C-2 and the substitution pattern of the double bond can modify the regio- and stereochemistry of the final products.