914399-98-7 Usage
General Description
FMoc-α-Me-Ser(tBu)-OH is a compound used in the field of organic chemistry as a building block for the synthesis of peptides and proteins. It is a derivative of serine with a tert-butyl (tBu) protecting group on the hydroxyl group and a fluorenylmethoxycarbonyl (FMoc) protecting group on the amino group. The α-methyl group on the serine residue can impart specific properties to the synthesized peptides, such as increased stability or altered biological activity. The tBu group protects the hydroxyl group from unwanted reactions during peptide synthesis, while the FMoc group allows for easy removal and subsequent coupling of the amino acid in solid-phase peptide synthesis. Overall, FMoc-α-Me-Ser(tBu)-OH is a versatile and important compound in the development of peptide-based drugs and biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 914399-98-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,3,9 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 914399-98:
(8*9)+(7*1)+(6*4)+(5*3)+(4*9)+(3*9)+(2*9)+(1*8)=207
207 % 10 = 7
So 914399-98-7 is a valid CAS Registry Number.
914399-98-7Relevant articles and documents
Efficient enantioselective synthesis of orthogonally protected (R)-α-alkylserines compatible with the solid phase peptide synthesis
Vassiliou, Stamatia,Yiotakis, Athanasios,Magriotis, Plato A.
, p. 7339 - 7341 (2006)
The Sch?llkopf methodology for the asymmetric synthesis of α-amino acids, which was previously not applicable to the construction of quaternary α-amino acids, has been rendered not only suitable but also practical for this purpose and applied to a highly efficient enantioselective synthesis of orthogonally protected (R)-α-alkylserines suitable for the solid phase synthesis.
