91454-65-8

Basic information

• Product Name: 7-[(CHLOROCARBONYL)METHOXY]-4-METHYLCOUMARIN
• Synonyms: CMMC;7-[(CHLOROCARBONYL)METHOXY]-4-METHYLCOUMARIN;7-chlorocarbonyl)methoxy-alpha-4-methylcoumarin;7-(CHLOROCARBONYL)METHOXY-ALPHA-4-METHYLCOUMARIN 98%;7-[(Chlorocarbonyl)methylcoumarin;7-[(Chlorocarbonyl)methoxy]-4-methylcoumarin,98%
• CAS NO: 91454-65-8
• Molecular Formula: C₁₂H₉ClO₄
• Molecular Weight: 252.65
• Product Categories: Coumarins
• Mol File: 91454-65-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 129 °C
• Boiling Point: 358.3°C (rough estimate)
• Flash Point: 175.5°C
• Appearance: /
• Density: 1.3293 (rough estimate)
• Vapor Pressure: 9.38E-07mmHg at 25°C
• Refractive Index: 1.4429 (estimate)
• CAS DataBase Reference: 7-[(CHLOROCARBONYL)METHOXY]-4-METHYLCOUMARIN(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(CHLOROCARBONYL)METHOXY]-4-METHYLCOUMARIN(91454-65-8)
• EPA Substance Registry System: 7-[(CHLOROCARBONYL)METHOXY]-4-METHYLCOUMARIN(91454-65-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 91454-65-8(Hazardous Substances Data)

Usage

Chemical Properties

blue-green to blue-grey powder

InChI:InChI=1/C12H9ClO4/c1-7-4-12(15)17-10-5-8(2-3-9(7)10)16-6-11(13)14/h2-5H,6H2,1H3

Upstream product

• 64700-15-8 7-(carboxymethoxy)-4-methylcoumarin 
• 5614-82-4 ethyl 2-(4-methyl-2-oxo-2-coumarin-7-yloxy)acetate 
• 90-33-5 7-hydroxy-4-methyl-chromen-2-one 
• 108-46-3 recorcinol 

Downstream Products

• 431040-67-4 2-[N-(4-methyl-2-oxobenzo[b]pyran-7-yloxyacetyl)-2-methoxyphenylaminomethylene]-2,3-dihydrobenzo[b]thiophen-3-one 
• 431040-69-6 2-[N-(4-methyl-2-oxobenzo[b]pyran-7-yloxyacetyl)-N-(2-p-tolylsulfonylaminophenyl)aminomethylene]-2,3-dihydrobenzo[b]thiophen-3-one 

Relevant articles and documents

A general synthesis of bis[coumarinyl] ethers: Synthesis of daphnoretin methyl ether

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Synthesis and anti-acetylcholinesterase activity of N-[(indolyl)ethyl)- coumarin-yloxy)]alkanamides

Novel coumarin-tryptamine systems attached through a linker were synthesised and evaluated in vitro against acetylcholinesterase by the classical Ellman's test.

Synthesis, X-ray characterization and biological evaluation of some new 2-(4-methy-2-oxo-2H-chromen-7yloxy) acetamide derivatives

Newly designed coumarinyloxy acetamide derivatives (7a-7n) were synthesized in good yields and characterised by advanced spectroscopic studies and the XRD studies indicated that no polymorphism is observed in the molecules. Synthesized coumarinyloxy aceta

A new convenient route to 2-oxoethoxycoumarins: Key intermediates in the synthesis of natural products

A new synthetic route to coumarinyloxyaldehydes starting from hydroxycoumarins is presented; these compounds, useful intermediates in the preparation of natural products such as geiparvarin and psoralens, are now available in excellent yields with a simple workup procedure. Moreover the reported route has been applied to dihydroxycoumarins.