91493-72-0

Basic information

• Product Name: 4'-NITRO-4-BIPHENYLSULFONIC ACID
• Synonyms: 4'-NITRO-4-BIPHENYLSULFONIC ACID
• CAS NO: 91493-72-0
• Molecular Formula: C₁₂H₉NO₅S
• Molecular Weight: 279.27
• Mol File: 91493-72-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 149-150 °C
• Appearance: /
• Density: 1.474g/cm³
• Refractive Index: 1.635
• PKA: -0.86±0.50(Predicted)
• CAS DataBase Reference: 4'-NITRO-4-BIPHENYLSULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-NITRO-4-BIPHENYLSULFONIC ACID(91493-72-0)
• EPA Substance Registry System: 4'-NITRO-4-BIPHENYLSULFONIC ACID(91493-72-0)

Safety Data

• Hazardous Substances Data: 91493-72-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H9NO5S/c14-13(15)11-5-1-9(2-6-11)10-3-7-12(8-4-10)19(16,17)18/h1-8H,(H,16,17,18)

Upstream product

• 92-93-3 1-phenyl-4-nitrobenzene 

Downstream Products

• 20443-75-8 4'-nitrobiphenyl-4-sulfonyl chloride 
• 857078-06-9 N-({4'-[(1-benzofuran-2-ylcarbonyl)amino]-1,1'-biphenyl-4-yl}sulfonyl)glycine t-butyl ester 

Relevant articles and documents

Biaryl sulfonamides and methods for using same

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

Synthesis of radiolabeled biphenylsulfonamide matrix metalloproteinase inhibitors as new potential PET cancer imaging agents

Novel matrix metalloproteinase (MMP) inhibitor radiotracers, (S)-3-methyl-2-(2′,3′,4′-methoxybiphenyl-4-sulfonylamino)- butyric acid [11C]methyl ester (1a-c), (S)-3-methyl-2-(2′,3′,4′-fluorobiphenyl-4-sulfonylamino)- butyric acid [11C]methyl ester (1d-f), and (S)-3-methyl-2-(4′-nitrobiphenyl-4-sulfonylamino)-butyric acid [11C]methyl ester (1g), a series of substituted biphenylsulfonamide derivatives, have been synthesized for evaluation as new potential positron emission tomography (PET) cancer imaging agents.