91533-23-2Relevant articles and documents
Green procedure for the synthesis of phthalazino[2,3-b]phthalazine-5,7,12, 14-tetraones
Habibi, Davood,Mahmoudi, Nosratollah,Marvi, Omid
, p. 3165 - 3171 (2007)
Different novel phthalazino[2,3-b]phthalazine-5,7,12,14-tetraones were synthesized in a simple and environmentally benign method from the reaction of phthalic anhydrides with semicarbazide or thiosemicarbazide using montmorillonite K-10 clay as solid heterogeneous acidic catalyst and microwaves under solvent-free conditions in good yields and short reaction times. Products were characterized by the elemental analysis, IR, NMR, and mass spectrometry. Copyright Taylor & Francis Group, LLC.
Synthesis and Biological Activity Evaluation of Differently Substituted 1,4-Dioxo-3,4-dihydrophthalazine-2(1H)-carboxamides and -carbothioamides
Cardia,Distinto,Maccioni,Bonsignore,DeLogu
, p. 1011 - 1015 (2007/10/03)
Differently substituted phthalic anhydrides can react either with semicarbazide or thiosemicarbazide to give respectively 1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carboxamides or 1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamides under mild conditions and generally with good yields. These compounds have been tested in order to evaluate their anti-microbial activity. Furthermore a new synthetic pathway to phtha-lazino[2,3-b]phthalazine-5,7,12,14-tetraone has been devised.