915396-55-3

Basic information

• Product Name: (S)-2-hydroxy-3-(4-hydroxyphenyl)-N-methoxy-N-methylpropanamide
• Synonyms: (S)-2-hydroxy-3-(4-hydroxyphenyl)-N-methoxy-N-methylpropanamide
• CAS NO: 915396-55-3
• Molecular Weight: 225.244
• Mol File: 915396-55-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-2-hydroxy-3-(4-hydroxyphenyl)-N-methoxy-N-methylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-hydroxy-3-(4-hydroxyphenyl)-N-methoxy-N-methylpropanamide(915396-55-3)
• EPA Substance Registry System: (S)-2-hydroxy-3-(4-hydroxyphenyl)-N-methoxy-N-methylpropanamide(915396-55-3)

Safety Data

• Hazardous Substances Data: 915396-55-3(Hazardous Substances Data)

Upstream product

• 6482-98-0 2-hydroxy-3-(4-hydroxyphenyl)propanoic acid 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 134197-95-8 (E)-3-(4-(benzyloxy)phenyl)-N-methoxy-N-methylacrylamide 
• 6272-45-3 (E)-4-benzyloxycinnamic acid 
• 7400-08-0 para-coumaric acid 
• 23508-35-2 (S)-2-hydroxy-3-(4-hydroxy-phenyl)-propionic acid 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 869093-41-4 (S)-4-(2-(benzhydryloxy)-3-(2,5-dimethoxyphenyl)-3-oxopropyl)phenyl pivalate 
• 869093-44-7 (S)-2,5-dimethoxyphenyl 2-hydroxy-3-(4-pivaloyloxyphenyl)propanoate 
• 869093-43-6 (S)-4-(3-(2,5-dimethoxyphenyl)-2-hydroxy-3-oxopropyl)phenyl pivalate 
• 123359-33-1 (S)-3-(4-hydroxyphenyl)-2-hydroxypropionyl methyl ester 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 58305-26-3 p-(bromomethyl)phenyl pivalate 
• 59012-91-8 2,2-dimethyl-propionic acid 4-hydroxymethyl-phenyl ester 

Downstream Products

• 169176-73-2 (S)-4-hydroxysattabacin 
• 1236191-25-5 (S)-2-((tert-butyldimethylsilyl)oxy)-3-(4-((tert-butyldimethylsilyl)oxy)phenyl)-N-methoxy-N-methylpropanamide 

Relevant articles and documents

Synthesis of Weinreb amides using diboronic acid anhydride-catalyzed dehydrative amidation of carboxylic acids

The first successful example of the direct synthesis of Weinreb amides using catalytic hydroxy-directed dehydrative amidation of carboxylic acids using the diboronic acid anhydride catalyst is described. The methodology is applicable to the concise syntheses of eight α-hydroxyketone natural products, namely, sattabacin, 4-hydroxy sattabacin, kurasoins A and B, soraphinols A and B, and circumcins B and C.

Concise, protecting group free total syntheses of (+)-sattabacin and (+)-4-hydroxysattabacin

The first asymmetric total syntheses of the antiviral natural products (+)-sattabacin and (+)-4-hydroxysattabacin are reported. Both total syntheses are remarkably concise and were completed without the use of protecting groups. These syntheses allowed the unambiguous assignment of the absolute configuration of both natural products. The syntheses of these natural products, which exhibit marked antiviral activity, are readily amenable to the preparation of structural analogs and progress in this regard is also reported.