91558-67-7 Usage
Chemical Structure
A piperidine ring with a sulfonyl group attached, a nitro group, and a methyl group on the benzene ring.
Application
Used in the field of pharmaceuticals and organic synthesis.
Interaction with Biological Systems
Has the potential to interact with biological systems due to its structural features.
Pharmacological Properties
May have pharmacological properties.
Synthesis
Commonly used in the synthesis of new drug candidates.
Material Development
May have applications in the development of new materials.
Use as a Reagent
Can be used as a reagent in organic reactions.
Context Dependent Properties
The specific properties and uses may vary depending on the context in which it is used.
Check Digit Verification of cas no
The CAS Registry Mumber 91558-67-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,5,5 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 91558-67:
(7*9)+(6*1)+(5*5)+(4*5)+(3*8)+(2*6)+(1*7)=157
157 % 10 = 7
So 91558-67-7 is a valid CAS Registry Number.
91558-67-7Relevant articles and documents
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5
Granchi, Carlotta,Roy, Sarabindu,Mottinelli, Marco,Nardini, Elisa,Campinoti, Fabio,Tuccinardi, Tiziano,Lanza, Mario,Betti, Laura,Giannaccini, Gino,Lucacchini, Antonio,Martinelli, Adriano,MacChia, Marco,Minutolo, Filippo
supporting information; experimental part, p. 7331 - 7336 (2012/02/04)
N-Hydroxyindole-2-carboxylates possessing sulfonamide-substituents at either position 5 or 6 were designed and synthesized. The inhibitory activities of these compounds against isoforms 1 and 5 of human lactate dehydrogenase were analysed, and Ki values of the most efficient inhibitors were determined by standard enzyme kinetic studies. Some of these compounds displayed state-of-the-art inhibitory potencies against isoform 5 (Ki values as low as 5.6 μM) and behaved as competitive inhibitors versus both the substrate and the cofactor.
