915707-69-6

Basic information

• Product Name: 2-Bromo-3-furoyl chloride
• Synonyms: 2-Bromo-3-furoyl chloride;2-Bromo-3-furoyl chloride 97%;2-Bromofuran-3-carbonyl chloride, 2-Bromo-3-(chlorocarbonyl)furan
• CAS NO: 915707-69-6
• Molecular Formula: C₅H₂BrClO₂
• Molecular Weight: 209.42518
• Mol File: 915707-69-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 207.1 °C at 760 mmHg
• Flash Point: 79 °C
• Appearance: /
• Density: 1.823 g/cm³
• Vapor Pressure: 0.23mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 2-Bromo-3-furoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-furoyl chloride(915707-69-6)
• EPA Substance Registry System: 2-Bromo-3-furoyl chloride(915707-69-6)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 915707-69-6(Hazardous Substances Data)

Usage

General Description

2-Bromo-3-furoyl chloride is an organic compound with the chemical formula C5H2BrClO2. It is a highly reactive and versatile chemical that is used in various industrial processes and organic synthesis. It is most commonly used as a reagent in the preparation of various furoyl derivatives, which are important intermediates in the pharmaceutical and agrochemical industries. 2-Bromo-3-furoyl chloride is known for its strong acylating capability, making it useful in the modification of various organic compounds. It is also a key building block in the synthesis of a wide range of bioactive molecules, including pharmaceuticals and biologically active compounds. Additionally, it is used in the production of specialty polymers and materials. Due to its reactivity and versatility, 2-Bromo-3-furoyl chloride is an important and widely used chemical in the field of organic chemistry.

InChI:InChI=1/C5H2BrClO2/c6-4-3(5(7)8)1-2-9-4/h1-2H

Upstream product

• 197846-05-2 2-bromofuran-3-carboxylic acid 
• 488-93-7 3-Furoic acid 

Downstream Products

• 197846-07-4 2-Bromo-furan-3-carboxylic acid phenylamide 

Relevant articles and documents

Photostable Helical Polyfurans

This report describes the design and synthesis of a new class of polyfurans bearing ester side chains. The macromolecules can be synthesized using catalyst-transfer polycondensation, providing precise control over molecular weight and molecular weight distribution. Such obtained furan ester polymers are significantly more photostable than their alkyl analogues owing to the electron-withdrawing nature of the attached subunit. Most interestingly, they spontaneously fold into a compact π-stacked helix, yielding a complex multilayer cylindrical nanoparticle with a hollow, rigid, conjugated core composed of the polyfuran backbone and a soft, insulating outer layer formed by the ester side chains. The length of polymer side chains dictates the outer diameter of such nanoparticles, which for the hexyl ester groups used in the present study is equal to ～2.3 nm. The inner cavity of the conjugated core is lined with oxygen atoms, which set its effective diameter to 0.4 nm. Furthermore, installation of bulkier, branched chiral ester side chains on the repeat unit yields structures that, upon change of solvent, can reversibly transition between an ordered chiral helical folded and disordered unfolded state.

Synthesis of 6-phenanthridinones and their heterocyclic analogues through palladium-catalyzed sequential aryl-aryl and N-aryl coupling

(Chemical Equation Presented) 6-Phenanthridinones and their heterocyclic analogues were synthesized through a one-pot procedure based on consecutive Pd-catalyzed aryl-aryl and N-aryl coupling from iodoarenes ortho-substituted by electron-releasing substituents and amides of o-bromoarene- and heteroarenecarboxylic acids.