91592-53-9

Basic information

• Product Name: C₅₃H₅₁ClN₅O₁₄P
• CAS NO: 91592-53-9
• Molecular Weight: 1048.44
• Mol File: 91592-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₃H₅₁ClN₅O₁₄P(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₃H₅₁ClN₅O₁₄P(91592-53-9)
• EPA Substance Registry System: C₅₃H₅₁ClN₅O₁₄P(91592-53-9)

Safety Data

• Hazardous Substances Data: 91592-53-9(Hazardous Substances Data)

Upstream product

• 91592-77-7 5’-O-(4,4’-dimethoxytrityl)thymidine 3’-(benzotrizol-1-yl 2-chlorophenyl phosphate) 
• 4836-13-9 N₄-benzoyl-2'-deoxycytidine 
• 80817-46-5 bis(benzotriazol-1-yl)(2-chlorophenyl)phosphate 

Relevant articles and documents

SYNTHESIS OF DNA FRAGMENTS BY THE HYDROXYBENZOTRIAZOLE PHOSPHOTRIESTER APPROACH

The application of the phosphorylating agent 2-chlorophenyl-o,o-bis--phosphate (HOBT-approach) for the introduction of 3'-5'-phosphotriester linkages between a properly 5'-protected (4,4'-dimethoxytrityl) deoxy-nucleoside and a deoxy-nucleoside having free OH groups is described.In this way, all sixteen partially-protected DNA dimers having a free 3'-OH group have been synthesized.The dimers thus obtained have been applied, using the HOBT-approach, to the synthesis of the DNA fragments d-CGCGCG, d-CGTACG and d-ATATTAATAAC.