915945-40-3

Basic information

• Product Name: 3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthaliMidyl)quinoline
• Synonyms: 3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthaliMidyl)quinoline;4-[(3-Chloro-4-fluorophenyl)aMino]-6-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-7-ethoxy-3-quinolinecarbonitrile
• CAS NO: 915945-40-3
• Molecular Formula: C26H16ClFN4O3
• Molecular Weight: 487
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 915945-40-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 674.7±65.0 °C(Predicted)
• Appearance: /
• Density: 1.52±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly, Heated)
• PKA: 3.77±0.50(Predicted)
• CAS DataBase Reference: 3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthaliMidyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthaliMidyl)quinoline(915945-40-3)
• EPA Substance Registry System: 3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthaliMidyl)quinoline(915945-40-3)

Safety Data

• Hazardous Substances Data: 915945-40-3(Hazardous Substances Data)

Upstream product

• 915945-39-0 (E/Z) 3-[3-ethoxy-4-(N-phthalimidyl)]anilino-N-(3-chloro-4-fluoro)phenyl-2-cyano-2-propenamide 

Relevant articles and documents

Method of preparing 3-cyano-quinolines and intermediates made thereby

The present invention relates to methods for preparing substituted 3-cyanoquinolines and intermediates obtained by the methods of the present invention. The methods of the invention comprise reacting an N-aryl-2-propanimide with phosphoryl chloride to produce the substituted 3-cyanoquinolines. The methods further comprise reacting arylamines, orthoformates and active methylenes to produce the N-aryl-2-propenamide.