915966-05-1

Basic information

• Product Name: 3-benzyloxy-2-propyl-estra-1,3,5(10)-triene-17β-ol
• Synonyms: 3-benzyloxy-2-propyl-estra-1,3,5(10)-triene-17β-ol
• CAS NO: 915966-05-1
• Molecular Weight: 404.593
• Mol File: 915966-05-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyloxy-2-propyl-estra-1,3,5(10)-triene-17β-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyloxy-2-propyl-estra-1,3,5(10)-triene-17β-ol(915966-05-1)
• EPA Substance Registry System: 3-benzyloxy-2-propyl-estra-1,3,5(10)-triene-17β-ol(915966-05-1)

Safety Data

• Hazardous Substances Data: 915966-05-1(Hazardous Substances Data)

Upstream product

• 113-38-2 estradiol dipropionate 
• 50-28-2 estradiol 
• 915965-99-0 propionic acid 3-hydroxy-2-propionyl-estra-1,3,5⁽¹⁰⁾-triene-17-yl ester 
• 915966-01-7 propionic acid 3-hydroxy-2-propyl-estra-1,3,5⁽¹⁰⁾-triene-17-yl ester 
• 915966-03-9 propionic acid 3-benzyloxy-2-propyl-estra-1,3,5⁽¹⁰⁾-triene-17-yl ester 

Relevant articles and documents

17β-HSD1 AND STS INHIBITORS

The present invention relates to novel substituted steroid derivatives which represent selectiv inhibitors of the 17β-hydroxysteroid dehydrogenase type I (17β-HSD1) and, in addition, which may represent inhibitors of the steroid sulphatase, as well as to their salts, to pharmaceutical preparations containing these compounds and to processes for the preparation of these compounds. Furthermore, the invention concerns the therapeutic use of said novel substituted steroid derivatives, particularly their use in the treatment or prevention of steroid hormone dependent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of 17β-hydroxysteroid dehydrogenase type I and/or steroid sulphatase enzymes and/or requiring the lowering of the endogenous 17β-estradiol concentration.