916159-68-7Relevant articles and documents
Chemoenzymatic synthesis and biological evaluation of ganglioside GM3 and lyso-GM3 as potential agents for cancer therapy
Li, Tingshen,Wang, Xiaodan,Dong, Peijie,Yu, Peng,Zhang, Yongmin,Meng, Xin
, (2021/09/07)
A highly efficient chemoenzymatic method for synthesizing ganglioside GM3 and lyso-GM3 was reported here. Enzymatic extension of the chemically synthesized lactosyl sphingosine using efficient one-pot multienzyme (OPME) reaction allowed glycosylation to b
3-O-SULFO-GALACTOSYLCERAMIDE ANALOGS AS ACTIVATORS OF TYPE II NKT CELLS AND USES THEREOF
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Paragraph 0068; 0095; 0098; 0116; 0117, (2019/10/19)
Disclosed is a compound of the formula (I) or (II): wherein a f are as described herein. The compounds are useful in the activation of Type II NKT cells and in treating cancer.
Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc4βCer
Santra, Abhishek,Li, Yanhong,Yu, Hai,Slack, Teri J.,Wang, Peng George,Chen, Xi
, p. 8280 - 8283 (2017/07/26)
A highly efficient chemoenzymatic method for synthesizing glycosphingolipids using α-Gal pentasaccharyl ceramide as an example is reported here. Enzymatic extension of the chemically synthesized lactosyl sphingosine using efficient sequential one-pot mult