916441-62-8

Basic information

• Product Name: [2-(5-bromo-2-methoxy-benzyloxymethoxy)-ethyl]-trimethyl-silane
• Synonyms: [2-(5-bromo-2-methoxy-benzyloxymethoxy)-ethyl]-trimethyl-silane
• CAS NO: 916441-62-8
• Molecular Weight: 347.324
• Mol File: 916441-62-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(5-bromo-2-methoxy-benzyloxymethoxy)-ethyl]-trimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(5-bromo-2-methoxy-benzyloxymethoxy)-ethyl]-trimethyl-silane(916441-62-8)
• EPA Substance Registry System: [2-(5-bromo-2-methoxy-benzyloxymethoxy)-ethyl]-trimethyl-silane(916441-62-8)

Safety Data

• Hazardous Substances Data: 916441-62-8(Hazardous Substances Data)

Upstream product

• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 80866-82-6 5-bromo-2-methoxy-benzyl alcohol 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 

Downstream Products

• 916441-73-1 2-[4-methoxy-3-(2-trimethylsilanyl-ethoxymethoxymethyl)-phenyl]-2-methyl-propionitrile 
• 916441-67-3 2-[4-methoxy-3-(2-trimethylsilanyl-ethoxymethoxymethyl)-phenyl]-2-methyl-propionic acid methyl ester 
• 916441-94-6 2-(3-(hydroxymethyl)-4-methoxyphenyl)-2-methylpropanenitrile 
• 916441-86-6 2-(3-hydroxymethyl-4-methoxy-phenyl)-2-methyl-propionic acid methyl ester 

Relevant articles and documents

Palladium catalyzed α-arylation of methyl isobutyrate and isobutyronitrile: an efficient synthesis of 2,5-disubstituted benzyl alcohol and amine intermediates

Several 2,5-disubstituted benzyl alcohols containing a functionalized t-butyl moiety were synthesized via palladium catalyzed α-arylation of methyl isobutyrate and butyronitrile on synthetically useful scales. The resulting benzyl alcohols could then be further elaborated to benzyl amines or other desirable intermediates.